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Cor.At®  
Mouse Cardiomyocytes

Cor.At® Cardiomyocytes are 100% pure primary-like cardiomyocytes derived from mouse embryonic stem cells (ES cells) or induced pluripotent stem cells (iPS cells) that are developed for academic and industrial cardiovascular research purposes. The kit includes 1 vial of cryopreserved mouse ES/iPSC-derived Cardiomyocytes (>1M/>5M cells/vial ES -derived; >1M/>3M iPSC-derived) and 1 bottle of Cor.At® Complete Culture Medium (250 mL). 

 

Product Data

Product Specifications

Catalog number

ES derived

Ax-C-MC01-1M– (>1 million cells)

Ax-C-MC01-5M– (>5 million cells)

 

iPSC-derived

Ax-C-MC04-1M – (>1 million cells)

Ax-C-MC04-3M – (>3 million cells)

Production Technology

Mouse ESC- and iPSC-derived, genetically modified cardiomyocytes; large scale production

Purity

Pure mouse cardiomyocytes selected by proprietary selection technology using the integrated puromycin selection cassette driven by the cardiac alpha MHC promoter.

Morphology

Fast and very robust beating (~120 – 240 BPM); fast development of contractile filaments and gap junctions

Assay window

Co.At® cardiomyocytes are ready for assay after 3 days; sensitive to hERG blocker in the first week of culture

Single cell action potential

Typical rodent-like short action potential (APD90 ~50 ms), fast phase 0 upstroke

Monolayer field potential

Very robust field potentials with very reproducible repolarization peak;

Recommended Storage

Cor.At® Complete Culture Medium: -20°C, after opening store at 2-8°C for a maximum of 4 weeks, no freeze-thaw cycles recommended

Cor.At® Cardiomyocytes: liquid nitrogen vapor phase