x

Translating an in vitro cellular system into a relevant clinical read-out requires a fully functional and validated model.

Cell models

Human iPSC-derived cells are functional in vitro models that provide meaningful clinical insights when utilized in physiologically relevant assays. They provide highly reproducible results and are available in a constant supply, which addresses key limitations of immortalized cell lines and cells derived from primary sources. Ncardia offers hiPSC-derived cell models though our standard catalog and custom cell manufacturing.

 

Catalog

Ncardia iPSC-derived cell models are used routinely in safety pharmacology, drug efficacy testing and cell therapy applications. These models are also utilized in Ncardia Services.

CARDIAC CELLS

Pluricyte Cardiomyocyte Kit

Human iPSC-derived cardiomyocytes produced without genetic modifications and cultured in a defined, serum-free medium for drug discovery.

CARDIOPLATE

Ncyte CardioPlate Maestro MEA 96

Analyzing drug effects in hiPSC-derived cardiomyocytes is easier with this ready-to-use Maestro plate containing Ncyte Cardiomyocytes.

NEURAL CELLS

Ncyte Astrocyte Kit

Cryopreserved hiPSC-derived astrocytes for neuronal co-cultures and applicable for neuro-inflammatory studies.

NEURAL CELLS

Ncyte Cortical Neuron Kit

Post mitotic, cortical layer committed and display a branching phenotype

NEURAL CELLS

Ncyte CNS Neuron Kit II

Comprised of two cell types of the human central nervous system (CNS): neurons (glutamatergic, GABAergic and dopaminergic) and astrocytes.

Manufacturing Services

Ncardia manufactures select cell models as dedicated batches for individual clients. This service provides the opportunity to customize critical cell model parameters to your drug discovery and cell therapy applications. Cell models can be assayed at Ncardia before delivery to qualify performance in your specific application. Quantities and fill formats are made to order as part of the service. The manufacturing process can be applied to an Ncardia iPSC line or your iPSC line. Additionally, customized medium and supplements can be included in the service.

CARDIAC CELLS

Atrial cardiomyocytes

Human iPS-derived atrial cardiomyoctes for safety, disease modeling, drug screening, and cell therapy.

CARDIAC CELLS

Ventricular cardiomyocytes

Human iPS-derived Cardiomyoctes for safety, disease modeling, drug screening, and cell therapy.

CARDIAC CELLS

Vascular Endothelial cells

Human iPS-derived Vascular Endothelial cells for vascular disease modeling, drug screening, and vascular tissue engineering.

CARDIAC CELLS

Vascular Smooth Muscle cells

Human iPS-derived Vascular Smooth Muscle cells for drug screening applications.

NEURAL CELLS

Peripheral neurons

Human iPSC-derived Peripheral neurons for structural and functional peripheral neurotoxicity assays, as well as neurotoxin screening.

 

Questions?

Do you have any questions about our hiPSC derived cell models? Our experts are ready to help you.