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Drug Discovery Solutions

Current drug development strategies are very expensive and lead to high drug attrition rates at a late stage of drug development. One major reason for low success rates is the lack of predictive preclinical models for efficacy and safety testing. At Ncardia we combine our cardiovascular and neural expertise with iPSC manufacturing to offer you predictive and translational assays at any throughput.

What we do best

At Ncardia we can think scientifically and creatively to solve your needs

 

 

End-to-end in vitro iPSC drug discovery services

 

 

In-house experts develop solutions based on your requirements

 

 

Full-service partner with 15 years of stem-cell drug discovery experience

 

 

Exclusive know-how and IP

DiscoverHIT Screening Platform

DiscoverHIT is a full service HTS-screening platform based on human induced pluripotent stem cell technology

Efficacy of compound libraries are assayed and screened on your specific disease model. This comprehensive service is comprised of four integrated modules; disease modeling, manufacturing, assay development and high throughput phenotypic screening.

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Drug Discovery Assays

For successful drug discovery studies, robust and reproducible assays are needed to test the effect of drug candidates throughout the drug discovery pipeline.

At Ncardia, we can apply hiPSC-derived (disease) models in a range of validated biochemistry- and cell-based assays to support your drug discovery activities.

Get inspired

Safety Services

Ncardia develops and delivers state of the art integrated cardiovascular services to enhance the assessment of cardiac safety and toxicity of drug candidates.

Our services are based on fully functional and validated hiPSC-derived cardiomyocytes that are manufactured under strict quality assurance.

Our safety services

Cell models

In order to translate an in vitro cellular model into the correct clinical interpretation of assay read-outs, a fully functional and validated model is needed.

This is assured by all of our fully functional human iPSC-derived cardiomyocytes and neural cells produced under a stringent quality manufacturing system.

Our cell models

Project process

1. Initial inquiry

Initial inquiry through the website, email or business development representative.

2. Consultation

Consultation with our cross-functional Ncardia team to discuss your request, understand your needs and set expectations correctly.

3. Expert team

Assignment of Lead Scientist, Project Manager and expert team to manage your custom request.

4. Project plan

For custom projects we will draft a detailed project plan including clear timelines and milestones.

5. Finetuning

The project plan is reviewed by you and finalized including your final input and a payment structure.

6. Execution

Execution of the project with regular interaction with you.

7. Delivery

A final report will be created and presented. At this stage there should be no surprises.

8. Feedback

We would love to hear your feedback and discuss your next project.