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At Ncardia we would like to hear all your ideas, challenges and questions, and bring those to a solution that fits your needs. To us, there are no limitations in what we can do for you.Contact us
Efficient assessment of drug safety and toxicity can be a complex and time consuming matter.
High quality – our safety pharmacology experts perform the studies on validated platforms
Save time - no assay optimization and data analysis needed – let our experts do this for you
Reliable – assays are based on fully functional and validated hiPSC-derived cardiomyocytes
Versatile – we offer a broad range of optimized assays on various platforms
Flexible – we will make sure to meet your specific needs
Standardized MEA safety profiling - running biweekly at Ncardia
Delivers an acute cardiac safety profile of your compounds following the current protocols of the CiPA initiative for microelectrode arrays (MEA) analysis.
Predictive in vitro safety assessment of drug candidates using functional human endothelial cells.
Assessment of drug induced vascular leakage using high-content, real-time and label-free impedance-based technology that monitors changes in electrical impedance across the endothelial cell monolayer.
Calcium Transient Analysis of Drug Effects
High-throughput screening of drug effects on cardiomyocyte electrophysiology by analyzing the intracellular calcium transients.
Acute and long-term cytotoxicity analysis by impedance.
Delivers a cardiac safety profile based on label-free impedance analysis of your compounds using hiPSC-derived cardiomyocytes.
Structural toxicity analysis
Delivers a structural cardiotoxicity profile of your compounds based on the detection of cardiac specific biomarkers like Troponin I release by hiPSC-derived cardiomyocytes.
Multiplex of functional and structural cardiotoxicity
A multiparametric approach to deliver an extensive cardiotoxicity profile of your compounds. This service includes an analysis by impedance (contractility), electrophysiology and biomarker release (structural).
Did not find what you were looking for? Are you interested in a different cell model like endothelial cells, smooth muscle cells or neural cells? Or more interested in biochemical characterization of your cell model?
Let us know what your needs are and we will develop a customized service for you.