Whitepaper: Neuroinflammation study by combining human iPSC-derived astrocytes and HTRF

Chronic neuroinflammation, a feature common to neurodegenerative diseases such as Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis, may be responsive to therapeutic intervention. Recent research has identified glial cells as mediators of neurodegeneration, driving disease onset and progression.

The aim of neuroscience research in this area is to acquire an in-depth understanding of the chronological events that lead to neuroinflammation, in order to promote the neuroprotective pathways. This white paper demonstrates that Ncardia’s iPSC-derived astrocytes combined with HTRF cellular assays represent a straightforward and physiologically relevant solution for the study of neuroinflammation pathways.