Several disease models have contributed to advances in cardiac and neurological research. The development of new disease models is advancing iPSC differentiation techniques. As a result, more cell-relevant disease models are available to explore and allows us to unlock secrets of several diseases, including those for muscular diseases such as Duchenne's Muscular Dystrophy.
Nevertheless, implementation of iPSC-derived models in drug discovery projects involves several critical considerations. For instance, lineage specification of iPSCs to cell types that closely recapitulate key disease features and cell manufacturing at a commercial scale. Another critical step is reproducibility and development of high-throughput assays that measure the disease biology.
During the webinar - "Unlocking the secrets of muscular disease using iPSC models" - our senior scientist stem cell technology Mariana Argenziano will discuss the advantages, challenges, and solutions of implementing iPSC-technology into drug discovery and development for muscle disease modeling.
In this webinar, you will learn about:
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The advantages of iPSC-derived muscle disease models
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The critical considerations when implementing iPSC-based models
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The iPSC-based model of Duchenne's Muscular Dystrophy and its advantages and challenges.
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